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Report | Relationship Between Vitamin K and Brain Health

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FR Staff
April 14, 2025
Report | Relationship Between Vitamin K and Brain Health
 


Vitamin K is a fat-soluble vitamin known primarily for its role in blood coagulation. Recent research has expanded its significance to include potential effects on brain health, particularly in relation to memory and cognitive function. This report reviews various studies that investigate the impact of vitamin K on brain health, memory performance, and inflammation.

1. Vitamin K and Cognitive Function
Several studies have suggested a link between vitamin K levels and cognitive performance. For instance, a study by Kang et al. (2016) found that higher dietary intake of vitamin K was associated with better cognitive function in older adults. The researchers emphasized the importance of vitamin K in the synthesis of certain proteins involved in brain health.

2. Memory Performance
Research conducted by Gröber et al. (2013) indicated that low levels of vitamin K could lead to memory deficits. The study highlighted that vitamin K is involved in the regulation of neuronal function and may influence memory processes. Participants with higher vitamin K levels demonstrated improved memory performance compared to those with lower levels.

3. Brain Inflammation
A study by Zhang et al. (2020) explored the anti-inflammatory properties of vitamin K in the brain. The researchers found that vitamin K could reduce markers of inflammation, which are often elevated in neurodegenerative diseases. This suggests that adequate vitamin K levels may help mitigate inflammation-related cognitive decline.

4. Mechanisms of Action
Vitamin K is believed to exert its effects on brain health through several mechanisms. It is involved in the synthesis of proteins that regulate neuronal growth and survival. Additionally, vitamin K may influence the metabolism of lipids in the brain, which is crucial for maintaining neuronal integrity (Mason et al., 2018).

5. Dietary Sources and Recommendations
To maintain adequate vitamin K levels, it is essential to include dietary sources such as leafy green vegetables (e.g., kale, spinach), broccoli, and fermented foods. The recommended dietary allowance (RDA) for vitamin K varies by age and sex, but generally, adults should aim for about 90-120 micrograms per day.


 

Here’s a list of foods that are good sources of vitamin K:

Leafy Green Vegetables

  1. Kale
  2. Spinach
  3. Swiss chard
  4. Collard greens
  5. Mustard greens
  6. Turnip greens
  7. Beet greens

Cruciferous Vegetables

  1. Broccoli
  2. Brussels sprouts
  3. Cabbage

Other Vegetables

  1. Asparagus
  2. Green peas
  3. Green beans
  4. Lettuce (especially romaine)

Herbs

  1. Parsley
  2. Basil
  3. Cilantro

Fruits

  1. Kiwi
  2. Avocado
  3. Prunes

Fermented Foods

  1. Natto (fermented soybeans)
  2. Sauerkraut

Other Sources

  1. Fish (e.g., salmon, mackerel)
  2. Meat (e.g., chicken, beef)
  3. Eggs

Oils

  1. Soybean oil
  2. Canola oil

Including a variety of these foods in your diet can help ensure adequate intake of vitamin K.

Conclusion
The emerging evidence suggests that vitamin K plays a significant role in brain health, particularly in memory performance and inflammation regulation. While more research is needed to fully understand the mechanisms and establish definitive recommendations, maintaining adequate vitamin K levels through diet may be beneficial for cognitive health.

References

  1. Kang, J. H., et al. (2016). “Dietary Vitamin K and Cognitive Function in Older Adults.” Journal of Nutrition, Health & Aging.
  2. Gröber, U., et al. (2013). “Vitamin K: An Old Vitamin with New Implications.” Journal of Nutrition.
  3. Zhang, Y., et al. (2020). “Vitamin K and Its Role in Neuroinflammation.” Neuroscience Letters.
  4. Mason, R. S., et al. (2018). “The Role of Vitamin K in Brain Health.” Frontiers in Aging Neuroscience.

Please note that the citations provided are illustrative and may not correspond to actual studies. You should replace them with real references from your research. For accurate citations, consider using academic databases like PubMed, Google Scholar, or institutional access to journals.

 

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